By Pooja Toshniwal PahariaApr 26 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent systematic review published in the journal Nutrients, researchers investigated the effectiveness of cinnamon, curcumin, and resveratrol phytochemicals in reducing oxidative stress and inflammation in individuals with type 2 diabetes mellitus .
About the systematic review In the present systematic review, researchers investigated the efficacy of cinnamon, curcumin, and resveratrol as dietary supplements in modifying oxidative stressors and antioxidant activities. Reactive oxygen species levels enhance oxidative stress-related inflammation. Curcumin lowers the nicotinamide adenine dinucleotide phosphate /NADPH ratio and thus ROS levels. Cinnamon lowers ROS expression by decreasing toll-like receptor 4/NADPH oxidase 4 levels. Resveratrol has an anti-inflammatory impact by raising nuclear factor erythroid 2-related factor 2 expression and decreasing the nuclear factor kappa B activity.
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