Sugar substitute xylitol linked to increased risk of heart attack, stroke

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Sugar substitute xylitol is linked to increased risk of heart attack and stroke, according to a new study. The findings question the health risks of sugar alcohols even as their use trends upward.

Sugar alcohols such as xylitol and erythritol are widely used as sugar substitutes in processed foods, including these gummies, as well as candy, gums and baked goods.

The researchers cautioned that while these studies show that xylitol is linked with a higher risk of cardiovascular events, they do not show that it causes these events.Sugar alcohols such as xylitol and erythritol are widely used as sugar substitutes in processed foods such as candy, gums and baked goods. Sugar alcohols have fewer calories and carbs, and don’t cause sudden blood sugar spikes, studies show.

The results challenge the popular understanding of sugar alcohols such as xylitol and erythritol as healthy, natural sugar alternatives. People view them as natural because our bodies produce them as part of our energy metabolism; however, our cells produce them at much lower levels. When these sugar alcohols are manufactured, they are industrially prepared, using bacteria or yeast that’s put through brewing and fermentation processes to create a chemical that tricks our taste buds, Hazen said.

Another way of putting it is that, among the thousands of people Hazen sees in his preventive cardiology clinic, those whose cholesterol levels are in the top 25 percent have a 30 percent increase in the risk of a cardiovascular disease event compared with those whose cholesterol levels are in the bottom 25 percent.

While she believes the study needs repeating, it suggests that xylitol may not be benign. The benefits of artificial sweeteners in general are uncertain, she wrote.

 

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