She began a career as an actress in the TV series Echoes in 2011 and has hosted TV shows, including The Squeeze, What’s Hot, MTN Project Fame back stage, Trending on HipTV. She has also co-hosted The Headies award, and was a presenter of The Voice Nigeria. She recently launched her TV show, The Nancy Isime Show. In 2022, Isime starred in the Netflix original series Blood Sisters, playing the lead role of Kemi.
For me, the project was not just about me, but it is a collaborative effort of everybody, including the director, crew, producer and Netflix who ensured that we give our audience within and outside this space the real movie. We believe that nobody can tell our stories better than ourselves, so it was a job that we all had to give the best of ourselves to. I am truly happy that the audience appreciates the end product.