1 in 5 Brain Injury Trials Show Errors, Signs of Spin

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A new report shows that spin, including signs of exaggeration and mathematical errors, was seen in 21% of 150 randomized traumatic braininjury clinical trials published in leading medical journals. TBI

of 93 randomized clinical studies in cardiology, for example, found spin in 57% of abstracts and 67% of full texts. The lower number in the new study may be due to its especially conservative definition of spin, Martins said.Duke University Medical Center cardiologist Richard Krasuski, MD, who co-authored the 2019 study into spin in cardiology studies, toldthat the new analysis follows appropriate methodology and appears to be valid.

Why is there so much spin in medical research?"As an investigator, you always hope to positively impact patient health and outcomes, so there is a tendency to look at secondary analyses to have something good to emphasize," he said."This is an inherent trait in most of us, to find something good we can focus on. I do believe that much of this is subconscious and perhaps with noble intent.

"Always try to identify what the primary outcome of the study was at the time of the design and whether the investigators achieved their objective. As a reviewer, my own personal experience in research into spin makes me more cognizant of its existence, and I generally require authors to reword and tone down their message if it is not supported by the data."

 

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