, although it still remains to be proven whether this can help yield benefit in humans. While there are now a whole variety of off-the-shelf supplements that combine curcumin and piperine, there are still challenges for scientists looking to use it medically. One of these is that piperine
“Curcumin has seen a significant increase in use in athletics for recovery post-workouts and after games,” he says. “The idea is the same as with osteoarthritis and the goal is to reduce inflammation. We tend to avoid chronic NSAID use in athletes due to side-effects. The evidence seems to be positive, but once again there is still work to be done.”Photograph: Larisa Duka/Alamy
At the same time, oncologists at the University of Rochester Medical Center in New York state are running a trial to see whether curcumin supplemented with piperine can halt disease progression in patients with low-grade prostate cancer, and prevent them from requiring more aggressive treatment. Paultre says it is positive that further independent trials are being funded for curcumin because much of the research on the compound has been acquired through small studies that have been financed by the nutraceutical industry, which has created a perception of curcumin as a miracle cure. “Current studies still have a lot of potential bias in them,” he says. “Nutraceuticals do not have much regulatory oversight, and companies want to make a profit.
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